Plesk will be the control panel for V12 Business Hosting where it's the only webhosting control panel you'll need to build, secure, and run websites and applications in the cloud!
The main differences between Plesk and cPanel lie in their user interfaces and the web servers they support.
The Plesk user interface is similar to the WordPress admin panel and supports Linux & Windows servers.
cPanel has a graphical interface and is only compatible with Linux web servers.